| No carcinogenicity (ability to cause cancer) data for Avonex
® are available in animals or humans. Avonex ®
was not found to be mutagenic when tested in the
Ames Bacterial test, which is designed to assess whether agents
interact directly with, and cause damage to, cellular DNA.
However, in Acta Neurochir (Wien) 2002 Apr;144(4):365-8 [PubMed
link]
"Growth dynamics of meningiomas in patients with multiple sclerosis
treated with interferon: report of two cases."
Batay F, Al-Mefty O.
Department of Neurosurgery, University of Arkansas for
Medical Sciences, Little Rock, Arkansas, USA.
CONCLUSIONS: We reported the association of multiple sclerosis and
intracranial meningioma and observed the progression of the meningiomas
during interferon treatment. Although, we cannot exclude the coincidence
between the two diseases we discussed suspicious relationship between
the interferon treatment and the tumour progression.
|
